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・ Gastric inhibitory polypeptide receptor
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Gastric inhibitory polypeptide : ウィキペディア英語版
Gastric inhibitory polypeptide

Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of hormones.
GIP, along with glucagon-like peptide-1 (GLP-1), belongs to a class of molecules referred to as incretins.
==Synthesis and transport==
GIP is derived from a 153-amino acid proprotein encoded by the GIP gene and circulates as a biologically active 42-amino acid peptide. It is synthesized by K cells, which are found in the mucosa of the duodenum and the jejunum of the gastrointestinal tract.
Like all endocrine hormones, it is transported by blood.
Gastric inhibitory polypeptide receptors are seven-transmembrane proteins found on beta-cells in the pancreas.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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